Compound Detail
CHEMBL4856084
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Basic Information
| ChEMBL ID | CHEMBL4856084 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IWSZWDAJGJIATO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
400.5
MW (Da)
4.55
ALogP
4
HBA
2
HBD
71.2
PSA (Ų)
0.67
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 9.23
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor type 2 CHEMBL1804 | EC50 | 9.23 | 9.23 | 0.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor type 2 | EC50 | = | 0.59 | nM | 9.23 | Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition... | 34626901 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34626901 | 10.1016/j.bmc.2021.116424 | Somatostatin receptor type 2 | 1 |
| 34626901 | 10.1016/j.bmc.2021.116424 | Unchecked | 1 |
| 34626901 | 10.1016/j.bmc.2021.116424 | Voltage-gated inwardly rectifying potassium channel KCNH2 | 1 |
Data from ChEMBL 36 via Core Engine