Compound Detail
CHEMBL4857477
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Basic Information
| ChEMBL ID | CHEMBL4857477 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WRMKQFSFTFAZFP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
390.3
MW (Da)
4.41
ALogP
4
HBA
2
HBD
70.2
PSA (Ų)
0.63
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.09
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Epidermal growth factor receptor CHEMBL203 | IC50 | 7.09 | 7.09 | 81.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Epidermal growth factor receptor | IC50 | = | 81.0 | nM | 7.09 | Inhibition of EGFR (unknown origin) | 33771586 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33771586 | 10.1016/j.bmcl.2021.127987 | Epidermal growth factor receptor | 1 |
Data from ChEMBL 36 via Core Engine