Compound Detail
CHEMBL4860759
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Basic Information
| ChEMBL ID | CHEMBL4860759 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GTXCDOQYSKCDBP-UNJUUPHPSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
433.3
MW (Da)
3.41
ALogP
3
HBA
4
HBD
86.0
PSA (Ų)
0.56
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| MV4-11 CHEMBL613835 | IC50 | 7.21 | 7.21 | 61.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| MV4-11 | IC50 | = | 61.5 | nM | 7.21 | Antiproliferative activity against human MV4-11 cells incubated for 72 hrs by Ce... | 33797247 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33797247 | 10.1021/acs.jmedchem.0c02247 | No relevant target | 1 |
| 33797247 | 10.1021/acs.jmedchem.0c02247 | MV4-11 | 1 |
Data from ChEMBL 36 via Core Engine