Compound Detail
CHEMBL4861437
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4861437 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YPDPXLXQZBEHOG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
417.5
MW (Da)
4.88
ALogP
5
HBA
0
HBD
49.3
PSA (Ų)
0.52
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 7.5 | 7.5 | 32.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 32.0 | nM | 7.5 | Inhibition of GST-tagged recombinant RANKL/M-CSF-induced osteoclastogenesis in C... | 33158578 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33158578 | 10.1016/j.ejmech.2020.112982 | Unchecked | 6 |
Data from ChEMBL 36 via Core Engine