Compound Detail
CHEMBL4862021
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Basic Information
| ChEMBL ID | CHEMBL4862021 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KIASHLHEXMLQSS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
349.2
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Leishmania infantum CHEMBL612848 | EC50 | 5.19 | 5.19 | 6400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Leishmania infantum | EC50 | = | 6400.0 | nM | 5.19 | Antileishmanial activity against amastigote stage of Leishmania infantum MHOM/MA... | 34711050 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34711050 | 10.1021/acs.jmedchem.1c01437 | ADMET | 3 |
| 34711050 | 10.1021/acs.jmedchem.1c01437 | Peritoneal macrophage | 1 |
| 34711050 | 10.1021/acs.jmedchem.1c01437 | Leishmania infantum | 1 |
| 34711050 | 10.1021/acs.jmedchem.1c01437 | MRC5 | 1 |
Data from ChEMBL 36 via Core Engine