Compound Detail
CHEMBL4862426
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)[C@@H](C)O
Basic Information
| ChEMBL ID | CHEMBL4862426 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KFKKXIQPBCRCFD-FYYHEUGWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
13
Publications
0
Known Names
Molecular Properties
1445.7
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.6 | 4.6 | 25170.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 25170.0 | nM | 4.6 | Cytotoxicity against human glomerular mesangial cells incubated for 12 hrs by MT... | 34180670 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Escherichia coli | 4 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Klebsiella pneumoniae | 4 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | ADMET | 4 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Pseudomonas aeruginosa | 3 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Bacteria | 3 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Staphylococcus aureus | 1 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Bacillus subtilis | 1 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Enterococcus faecalis | 1 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Staphylococcus epidermidis | 1 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Acinetobacter baumannii | 1 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Erythrocyte | 1 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Unchecked | 1 |
| 34180670 | 10.1021/acs.jmedchem.1c00614 | Fungi | 1 |
Data from ChEMBL 36 via Core Engine