Compound Detail
CHEMBL4864629
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Basic Information
| ChEMBL ID | CHEMBL4864629 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | POOWANBBEHAILI-UHFFFAOYSA-N |
1
Targets
5
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
328.0
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 5 meas. best 5.03
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.03 | 4.79 | 9430.0 | 5 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 9430.0 | nM | 5.03 | Inhibition of bacterial Beta-lactamase KPC-2 (29 - 289) (unknown origin) express... | 33744439 |
| Unchecked | IC50 | = | 13130.0 | nM | 4.88 | Inhibition of bacterial Beta-lactamase VIM-1 (27 - 266) (unknown origin) express... | 33744439 |
| Unchecked | IC50 | = | 14930.0 | nM | 4.83 | Inhibition of bacterial Beta-lactamase SFH-1 (3 - 234) expressed in Escherichia ... | 33744439 |
| Unchecked | IC50 | = | 23970.0 | nM | 4.62 | Inhibition of bacterial New Delhi metallo-beta-lactamase 1 (1- 270) (unknown ori... | 33744439 |
| Unchecked | IC50 | = | 25870.0 | nM | 4.59 | Inhibition of bacterial Beta-lactamase AmpC (20 - 377) (unknown origin) expresse... | 33744439 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33744439 | 10.1016/j.bmcl.2021.127956 | Unchecked | 6 |
| 33744439 | 10.1016/j.bmcl.2021.127956 | Beta-lactamase TEM | 1 |
Data from ChEMBL 36 via Core Engine