Compound Detail
CHEMBL4867885
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CCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)CC[C@H](NC(=O)CCCCCCCCCCC)C(=O)O)C(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)O)C(=O)O
Basic Information
| ChEMBL ID | CHEMBL4867885 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IWLJBTTUWHVDCA-SVWSIEHRSA-N |
1
Targets
1
Activities
1
Assay Types
2
PK Parameters
4
Publications
0
Known Names
Molecular Properties
1059.3
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 11.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glucagon-like peptide 1 receptor CHEMBL1784 | EC50 | 11.0 | 11.0 | 0.0 | 1 |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| Ka | 5.97 | 10^2/Ms | Homo sapiens |
| Ke | 1.44 | 10^-5M | Homo sapiens |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glucagon-like peptide 1 receptor | EC50 | = | 0.0101 | nM | 11.0 | Activation of GLP1R (unknown origin) CRE-bla expressed in CHO-K1 cells assessed ... | 34216986 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34216986 | 10.1016/j.bmc.2021.116291 | Glucagon-like peptide 1 receptor | 4 |
| 34216986 | 10.1016/j.bmc.2021.116291 | Mus musculus | 3 |
| 34216986 | 10.1016/j.bmc.2021.116291 | Albumin | 1 |
| 34216986 | 10.1016/j.bmc.2021.116291 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine