Compound Detail
CHEMBL488259
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Basic Information
| ChEMBL ID | CHEMBL488259 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RDGDIVQKAVGUJX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
328.2
MW (Da)
4.36
ALogP
3
HBA
0
HBD
33.5
PSA (Ų)
0.84
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.69
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus 1 CHEMBL378 | EC50 | 6.69 | 6.69 | 204.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus 1 | EC50 | = | 204.0 | nM | 6.69 | Antiviral activity against HIV1 3B in human MT4 cells | 17870209 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17870209 | 10.1016/j.ejmech.2007.07.017 | Human immunodeficiency virus 1 | 1 |
| 18947995 | 10.1016/j.bmcl.2008.10.023 | Replicase polyprotein 1ab | 1 |
| 18947995 | 10.1016/j.bmcl.2008.10.023 | Hepatitis C virus | 1 |
| 18947995 | 10.1016/j.bmcl.2008.10.023 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine