Compound Detail
CHEMBL490677
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Basic Information
| ChEMBL ID | CHEMBL490677 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RHWSTNZSAHNRGX-SSZFMOIBSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
377.5
MW (Da)
4.18
ALogP
5
HBA
0
HBD
46.6
PSA (Ų)
0.29
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 10000.0 | nM | 5.0 | Inhibition of 6-His tagged recombinant c-Myc353-437 gene binding to Max(S) prote... | 19215087 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19215087 | 10.1021/jm801278g | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine