Compound Detail
CHEMBL491507
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Basic Information
| ChEMBL ID | CHEMBL491507 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZGDQNKAQIJBCTN-UHFFFAOYSA-N |
| Parent Compound | CHEMBL1187146 |
| Active Moiety | CHEMBL1187146 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
457.6
MW (Da)
5.00
ALogP
3
HBA
0
HBD
26.8
PSA (Ų)
0.50
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 8.71
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor type 1 CHEMBL4652 | Kd | 8.71 | 8.71 | 1.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor type 1 | Kd | = | 1.95 | nM | 8.71 | Binding affinity to rat sst1 receptor | 19208473 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19208473 | 10.1016/j.bmcl.2009.01.072 | Somatostatin receptor type 1 | 1 |
Data from ChEMBL 36 via Core Engine