Compound Detail
CHEMBL491841
LYCOGALIC ACID A Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL491841 |
| Name | LYCOGALIC ACID A |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FZDVNXHYGMEEDT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
385.4
MW (Da)
4.71
ALogP
2
HBA
5
HBD
122.0
PSA (Ų)
0.31
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transcription factor HES-1 CHEMBL1075292 | IC50 | 5.22 | 5.22 | 6000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transcription factor HES-1 | IC50 | = | 6000.0 | nM | 5.22 | Inhibition of Cy3-labeled mouse recombinant Hes1 (3-281) dimer formation express... | 19716294 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19716294 | 10.1016/j.bmcl.2009.07.146 | Transcription factor HES-1 | 3 |
| 18842058 | 10.1021/np800286d | Herpesviridae sp. | 1 |
Data from ChEMBL 36 via Core Engine