Compound Detail
CHEMBL493560
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Basic Information
| ChEMBL ID | CHEMBL493560 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YVMLLWOOFXSHOL-AATRIKPKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
326.4
MW (Da)
1.79
ALogP
5
HBA
3
HBD
104.2
PSA (Ų)
0.53
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.99
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase pim-2 CHEMBL4523 | IC50 | 5.99 | 5.99 | 1020.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase pim-2 | IC50 | = | 1020.0 | nM | 5.99 | Inhibition of Pim2 | 19256503 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19256503 | 10.1021/jm801242y | Serine/threonine-protein kinase pim-2 | 1 |
Data from ChEMBL 36 via Core Engine