Compound Detail
CHEMBL494622
FLURPIRIDAZ 💊 Approved Drug
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
💊 Approved Drug
Basic Information
| ChEMBL ID | CHEMBL494622 |
| Name | FLURPIRIDAZ |
| Phase | Approved |
| Structure Type | MOL |
| InChI Key | RMXZKEPDYBTFOS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
368.8
MW (Da)
3.72
ALogP
5
HBA
0
HBD
53.4
PSA (Ų)
0.70
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| First Approval | 2024 |
| Availability | Prescription |
| Chirality | Achiral |
Activity Summary
IC50 1 meas. best 7.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 7.96 | 7.96 | 11.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 11.0 | nM | 7.96 | Inhibition of mitochondrial complex 1 in bovine heart mitochondria assessed as e... | 18422306 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18422306 | 10.1021/jm701443n | ADMET | 4 |
| 18422306 | 10.1021/jm701443n | Heart | 2 |
| 18422306 | 10.1021/jm701443n | Lung | 2 |
| 18422306 | 10.1021/jm701443n | Liver | 2 |
| 18422306 | 10.1021/jm701443n | Femur | 2 |
| 18422306 | 10.1021/jm701443n | Blood | 2 |
| 23608108 | 10.1016/j.bmc.2013.03.080 | Liver | 2 |
| 18422306 | 10.1021/jm701443n | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine