Compound Detail
CHEMBL497916
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Basic Information
| ChEMBL ID | CHEMBL497916 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IUARBIFUFCHZPF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
421.9
MW (Da)
4.17
ALogP
4
HBA
4
HBD
107.0
PSA (Ų)
0.35
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.03
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Coagulation factor X CHEMBL244 | IC50 | 7.03 | 7.03 | 93.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Coagulation factor X | IC50 | = | 93.0 | nM | 7.03 | Inhibition of Factor 10a | 19297158 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19297158 | 10.1016/j.bmcl.2009.02.114 | Coagulation factor X | 1 |
Data from ChEMBL 36 via Core Engine