Compound Detail
CHEMBL497955
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Basic Information
| ChEMBL ID | CHEMBL497955 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GMBLMUZJVSLMTG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
364.9
MW (Da)
5.07
ALogP
2
HBA
2
HBD
33.3
PSA (Ų)
0.73
QED
1
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.64 | 5.64 | 2300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 2300.0 | nM | 5.64 | Inhibition of glucose-induced insulin secretion in Wistar rat pancreatic beta is... | 18406154 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18406154 | 10.1016/j.bmc.2008.03.065 | Molecular identity unknown | 7 |
| 18406154 | 10.1016/j.bmc.2008.03.065 | Unchecked | 3 |
| 18406154 | 10.1016/j.bmc.2008.03.065 | Aorta | 2 |
Data from ChEMBL 36 via Core Engine