Compound Detail
CHEMBL500557
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Basic Information
| ChEMBL ID | CHEMBL500557 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FQUDPIIGGVBZEQ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
131.2
MW (Da)
0.22
ALogP
2
HBA
2
HBD
50.4
PSA (Ų)
0.30
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosinase CHEMBL3318 | IC50 | 7.07 | 7.07 | 86.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosinase | IC50 | = | 86.0 | nM | 7.07 | Inhibition of mushroom tyrosinase | 18524420 |
| Tyrosinase | IC50 | = | 86.0 | nM | 7.07 | Inhibition of mushroom tyrosinase | 19800229 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18524420 | 10.1016/j.ejmech.2008.04.002 | Tyrosinase | 1 |
| 19800229 | 10.1016/j.bmcl.2009.09.018 | Tyrosinase | 1 |
Data from ChEMBL 36 via Core Engine