Compound Detail
CHEMBL500700
QUADRANOSIDE V Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL500700 |
| Name | QUADRANOSIDE V |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XNXMFRGRMHPZKN-JJPABSQASA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
664.8
MW (Da)
1.33
ALogP
11
HBA
8
HBD
197.4
PSA (Ų)
0.20
QED
3
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte CHEMBL3140324 | IC50 | 4.52 | 4.52 | 30200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte | IC50 | = | 30200.0 | nM | 4.52 | Hepatoprotective activity against D-GaIN/TNFalpha-induced cell death in mouse he... | 29353722 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10785422 | 10.1021/np990581+ | Hepatocyte | 4 |
| 29353722 | 10.1016/j.ejmech.2018.01.011 | Hepatocyte | 2 |
| 11277757 | 10.1021/np000486x | Hepatocyte | 1 |
Data from ChEMBL 36 via Core Engine