Compound Detail
CHEMBL506355
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL506355 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZBZKCPGSZOLGGP-LGRMDKJXSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
234.3
MW (Da)
2.71
ALogP
2
HBA
1
HBD
37.3
PSA (Ų)
0.70
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.06
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus 1 CHEMBL378 | IC50 | 4.06 | 4.06 | 88000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus 1 | IC50 | = | 88000.0 | nM | 4.06 | Antiviral activity against HIV1 3B infected in human HOG.R5 assessed as inhibiti... | 12608862 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12608862 | 10.1021/np020379y | ADMET | 2 |
| 12608862 | 10.1021/np020379y | Human immunodeficiency virus 1 | 1 |
| 12608862 | 10.1021/np020379y | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine