Compound Detail
CHEMBL506553
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O
Basic Information
| ChEMBL ID | CHEMBL506553 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | CBSXZYWGVAQSHI-RUKUCZSXSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
3157.5
MW (Da)
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 10.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Galanin receptor type 1 CHEMBL4894 | IC50 | 10.1 | 10.1 | 0.1 | 1 |
| Galanin receptor type 2 CHEMBL3176 | IC50 | 8.59 | 8.59 | 2.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Galanin receptor type 1 | IC50 | = | 0.079 | nM | 10.1 | Displacement of [125I]galanin from human recombinant GAL1 receptor expressed in ... | 27876250 |
| Galanin receptor type 2 | IC50 | = | 2.6 | nM | 8.59 | Displacement of [125I]galanin from human recombinant GAL2 receptor expressed in ... | 27876250 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27876250 | 10.1016/j.bmc.2016.11.014 | Galanin receptor type 1 | 1 |
| 27876250 | 10.1016/j.bmc.2016.11.014 | Galanin receptor type 2 | 1 |
Data from ChEMBL 36 via Core Engine