Compound Detail
CHEMBL507707
NOREUGENIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL507707 |
| Name | NOREUGENIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NCUJRUDLFCGVOE-UHFFFAOYSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
11
Publications
0
Known Names
Molecular Properties
192.2
MW (Da)
1.51
ALogP
4
HBA
2
HBD
70.7
PSA (Ų)
0.66
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.31
IC50 1 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus 1 CHEMBL378 | EC50 | 4.31 | 4.31 | 49000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus 1 | EC50 | = | 49000.0 | nM | 4.31 | Antiviral activity against HIV1 3B infected in human H9 cells assessed as inhibi... | 8158164 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32790311 | 10.1021/acs.jnatprod.0c00587 | Candida albicans | 2 |
| 32790311 | 10.1021/acs.jnatprod.0c00587 | Cryptococcus neoformans | 2 |
| 15203173 | 10.1016/j.bmcl.2004.04.062 | Maltase-glucoamylase | 1 |
| 15203173 | 10.1016/j.bmcl.2004.04.062 | Sucrase-isomaltase, intestinal | 1 |
| 8158164 | 10.1021/np50103a006 | H9 | 1 |
| 8158164 | 10.1021/np50103a006 | Human immunodeficiency virus 1 | 1 |
| 8158164 | 10.1021/np50103a006 | ADMET | 1 |
| 19405508 | 10.1021/np8006342 | A549 | 1 |
| 19405508 | 10.1021/np8006342 | MCF7 | 1 |
| 19405508 | 10.1021/np8006342 | HT-29 | 1 |
| 21542597 | 10.1021/np1008575 | Mycobacterium tuberculosis | 1 |
Data from ChEMBL 36 via Core Engine