Compound Detail
CHEMBL5083253
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Basic Information
| ChEMBL ID | CHEMBL5083253 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HZBZMMKJEWMGTE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
378.4
MW (Da)
2.90
ALogP
4
HBA
1
HBD
82.6
PSA (Ų)
0.89
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.14
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| BaF3 CHEMBL614524 | IC50 | 5.14 | 5.14 | 7230.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| BaF3 | IC50 | = | 7230.0 | nM | 5.14 | Antiproliferative activity against mouse BaF3 cells expressing CD74 fused TRKA a... | 34871843 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34871843 | 10.1016/j.ejmech.2021.114022 | BaF3 | 1 |
Data from ChEMBL 36 via Core Engine