Compound Detail
CHEMBL5090832
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5090832 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MZVBGPUVDNCSMM-UHFFFAOYSA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
282.2
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 6.81
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.81 | 6.4325 | 155.0 | 4 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 155.0 | nM | 6.81 | Inhibition of wild type Candida albicans Fructose-1,6-Bisphosphate Aldolase tran... | 35099959 |
| Unchecked | IC50 | = | 227.0 | nM | 6.64 | Inhibition of Candida albicans Fructose-1,6-Bisphosphate Aldolase C157S mutant t... | 35099959 |
| Unchecked | IC50 | = | 303.0 | nM | 6.52 | Inhibition of Candida albicans Fructose-1,6-Bisphosphate Aldolase C111S mutant t... | 35099959 |
| Unchecked | IC50 | = | 1754.0 | nM | 5.76 | Inhibition of Candida albicans Fructose-1,6-Bisphosphate Aldolase C292S mutant t... | 35099959 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35099959 | 10.1021/acs.jmedchem.1c02102 | Unchecked | 7 |
Data from ChEMBL 36 via Core Engine