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Compound Detail

CHEMBL5095475

PALOPEGTERIPARATIDE
💊 Approved Drug
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💊 Approved Drug
No structure available
ChEMBL ↗

Basic Information

ChEMBL ID CHEMBL5095475
Name PALOPEGTERIPARATIDE
Phase Approved
Structure Type SEQ
Therapeutic ✓ Yes
Active Moiety CHEMBL525610

Known Names

ACP-014 Mpeg 40000-teriparatide Palopegteriparatide TransCon PTH Transcon pth (1-34) Yorvipath
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
6
Known Names
1
Indications
2
Mechanisms

Drug Information

Molecule Type Protein
First Approval 2023
Availability Prescription
Chirality Single Enantiomer

Routes of Administration

Parenteral

Flags

Prodrug
USAN Stem -peg-; -tide
USAN Year 2022

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
Parathyroid hormone receptor agonist AGONIST Parathyroid hormone/parathyroid hormone-related peptide receptor ✓ ✓
Parathyroid hormone receptor agonist AGONIST Parathyroid hormone/parathyroid hormone-related peptide receptor ✓ ✓

Indications

Hypoparathyroidism

ATC Classification

H05AA05
palopegteriparatide
Level 1: SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
Level 2: CALCIUM HOMEOSTASIS

Data from ChEMBL 36 via Core Engine