Compound Detail
CHEMBL510112
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL510112 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KABWMLBFENPJRD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
474.5
MW (Da)
4.50
ALogP
7
HBA
2
HBD
94.6
PSA (Ų)
0.38
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte growth factor receptor CHEMBL3717 | Ki | 8.52 | 8.52 | 3.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte growth factor receptor | Ki | = | 3.0 | nM | 8.52 | Inhibition of human activated c-Met by PK/LDH coupled kinetic assay | 17964000 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17964000 | 10.1016/j.ejmech.2007.08.011 | Hepatocyte growth factor receptor | 1 |
Data from ChEMBL 36 via Core Engine