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Compound Detail

CHEMBL51024

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O=C(O[C@H]1[C@@H](c2cc(O)c(O)c(O)c2)Oc2cc(O)cc(O)c2[C@@H]1SCCO)c1cc(O)c(O)c(O)c1

Basic Information

ChEMBL ID CHEMBL51024
Phase Preclinical
Structure Type MOL
InChI Key UHHBMJFEBOOKPB-VJBWXMMDSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

534.5
MW (Da)
2.46
ALogP
13
HBA
9
HBD
217.6
PSA (Ų)
0.16
QED
3
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C24H22O12S
MW 534.50
Aromatic Rings 3
Heavy Atoms 37
NP-Likeness 1.44

Activity Summary

IC50 1 meas. best 4.69

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 4.69 4.69 20500.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked IC50 = 20500.0 nM 4.69 Inhibitory activity against lipid peroxidation of egg-phosphatidylcholine (PC) l... 9873437

Literature References

PubMed DOI Target Context # Activities
9873437 10.1016/s0960-894x(98)00311-4 Unchecked 2
9873437 10.1016/s0960-894x(98)00311-4 No relevant target 1

Data from ChEMBL 36 via Core Engine