Compound Detail
CHEMBL516513
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Basic Information
| ChEMBL ID | CHEMBL516513 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YSXQEHHKJXNICL-ZDUSSCGKSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
343.4
MW (Da)
2.35
ALogP
6
HBA
3
HBD
88.0
PSA (Ų)
0.74
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 4.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| SF-268 CHEMBL613977 | EC50 | 4.1 | 4.1 | 80200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| SF-268 | EC50 | = | 80200.0 | nM | 4.1 | Cytotoxicity against human SF-268 after 3 days by SRB assay | 15730238 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15730238 | 10.1021/np0496587 | MCF7 | 1 |
| 15730238 | 10.1021/np0496587 | NCI-H460 | 1 |
| 15730238 | 10.1021/np0496587 | SF-268 | 1 |
| 15730238 | 10.1021/np0496587 | Artemia | 1 |
| 15730238 | 10.1021/np0496587 | Micrococcus luteus | 1 |
| 15730238 | 10.1021/np0496587 | Mycolicibacterium smegmatis | 1 |
| 15730238 | 10.1021/np0496587 | Saccharomyces cerevisiae | 1 |
| 15730238 | 10.1021/np0496587 | Aspergillus niger | 1 |
Data from ChEMBL 36 via Core Engine