Compound Detail
CHEMBL5169957
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Basic Information
| ChEMBL ID | CHEMBL5169957 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HVOURTGJDCOIGM-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
440.6
MW (Da)
4.16
ALogP
9
HBA
1
HBD
90.4
PSA (Ų)
0.62
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 8.8 | 8.8 | 1.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 1.585 | nM | 8.8 | Displacement of [3H]-Rolipram from full-length recombinant human PDE4 expressed ... | 35144038 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35144038 | 10.1016/j.ejmech.2022.114170 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine