Compound Detail
CHEMBL5172000
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Basic Information
| ChEMBL ID | CHEMBL5172000 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JCDSCEOIUDLLDC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
310.4
MW (Da)
4.41
ALogP
3
HBA
2
HBD
63.4
PSA (Ų)
0.75
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily KQT member 2 CHEMBL2476 | EC50 | 5.07 | 5.07 | 8590.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily KQT member 2 | EC50 | = | 8590.0 | nM | 5.07 | Agonist activity at Kv7.2 (unknown origin) assessed as shifting of voltage depen... | 35671848 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35671848 | 10.1016/j.bmcl.2022.128841 | Potassium voltage-gated channel subfamily KQT member 2 | 3 |
| 35671848 | 10.1016/j.bmcl.2022.128841 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine