Compound Detail
CHEMBL5178591
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Basic Information
| ChEMBL ID | CHEMBL5178591 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LXMUATZYKBCNBI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
446.1
MW (Da)
5.64
ALogP
2
HBA
2
HBD
41.1
PSA (Ų)
0.51
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.08
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Influenza A virus CHEMBL613740 | EC50 | 7.08 | 7.08 | 83.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Influenza A virus | EC50 | = | 83.0 | nM | 7.08 | Antiviral activity against influenza A virus H5N1 infected in dog MDCK cells ass... | 35212527 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35212527 | 10.1021/acs.jmedchem.1c01257 | Influenza A virus | 1 |
| 35212527 | 10.1021/acs.jmedchem.1c01257 | MDCK | 1 |
| 35212527 | 10.1021/acs.jmedchem.1c01257 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine