Compound Detail
CHEMBL518285
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL518285 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IRLOQYRDNSOUOJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
413.5
MW (Da)
5.79
ALogP
3
HBA
3
HBD
82.5
PSA (Ų)
0.39
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.39
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Thrombopoietin receptor CHEMBL1864 | EC50 | 7.39 | 7.39 | 41.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Thrombopoietin receptor | EC50 | = | 41.0 | nM | 7.39 | Agonist activity at human thrombopoietin receptor in Ba/F3 cells assessed as act... | 18778936 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18778936 | 10.1016/j.bmcl.2008.08.068 | Thrombopoietin receptor | 2 |
Data from ChEMBL 36 via Core Engine