Compound Detail
CHEMBL5184204
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Basic Information
| ChEMBL ID | CHEMBL5184204 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YZRLKDBJPNLHPV-WMSVGEIISA-N |
| Parent Compound | CHEMBL5222117 |
| Active Moiety | CHEMBL5222117 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
404.5
MW (Da)
3.69
ALogP
6
HBA
1
HBD
61.8
PSA (Ų)
0.46
QED
0
Ro5 Violations
15
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 8.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Kd | 8.43 | 8.43 | 3.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Kd | = | 3.7 | nM | 8.43 | Binding affinity to amyloid beta (unknown origin) | 35759679 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35759679 | 10.1021/acs.jmedchem.1c01619 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine