Compound Detail
CHEMBL5192335
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5192335 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JUTGZQYBXRMUFP-VAWYXSNFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
309.4
MW (Da)
4.38
ALogP
3
HBA
1
HBD
42.2
PSA (Ų)
0.85
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human alphaherpesvirus 2 CHEMBL370 | EC50 | 6.57 | 6.57 | 270.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human alphaherpesvirus 2 | EC50 | = | 270.0 | nM | 6.57 | Antiviral activity against HSV-2 infected in African green monkey Vero cells ass... | 35635945 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35635945 | 10.1016/j.ejmech.2022.114443 | Human alphaherpesvirus 2 | 4 |
| 35635945 | 10.1016/j.ejmech.2022.114443 | Human alphaherpesvirus 1 | 2 |
| 35635945 | 10.1016/j.ejmech.2022.114443 | ADMET | 2 |
| 35635945 | 10.1016/j.ejmech.2022.114443 | Vero | 1 |
| 35635945 | 10.1016/j.ejmech.2022.114443 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine