Compound Detail
CHEMBL5199291
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Basic Information
| ChEMBL ID | CHEMBL5199291 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BKTBRJMYHRKCFT-CQSZACIVSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
309.4
MW (Da)
4.43
ALogP
3
HBA
2
HBD
41.5
PSA (Ų)
0.88
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 7.7 | 7.7 | 20.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 20.0 | nM | 7.7 | Antiprotozoal activity against Chloroquine-resistant Plasmodium falciparum K1 as... | 33901399 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33901399 | 10.1021/acs.jmedchem.1c00483 | Unchecked | 4 |
| 33901399 | 10.1021/acs.jmedchem.1c00483 | Plasmodium falciparum | 1 |
Data from ChEMBL 36 via Core Engine