Compound Detail
CHEMBL5199483
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Basic Information
| ChEMBL ID | CHEMBL5199483 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CSYJKVLAIVFBBK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
331.4
MW (Da)
2.55
ALogP
6
HBA
1
HBD
84.1
PSA (Ų)
0.67
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.06
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Lysine-specific demethylase 5C CHEMBL2163176 | IC50 | 8.06 | 8.06 | 8.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Lysine-specific demethylase 5C | IC50 | = | 8.8 | nM | 8.06 | Inhibition of N-terminal FLAG/His-tagged full-length human KDM5C (2 to 1560 resi... | 35101649 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35101649 | 10.1016/j.ejmech.2022.114143 | Lysine-specific demethylase 5C | 1 |
Data from ChEMBL 36 via Core Engine