Lysine-specific demethylase 5C · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P41229. Use UniProt P41229 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P41229 as the stable identity anchor, then attach disease evidence before program review.
Lysine-specific demethylase 5C
Review this target as Lysine-specific demethylase 5C, mapped to UniProt P41229. Sequence length is 1560 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Lysine-specific demethylase 5C as ChEMBL target CHEMBL2163176, mapped to UniProt P41229. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Lysine-specific demethylase 5C |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P41229 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lysine-specific demethylase 5C |
| UniProt Accession | P41229 |
| Component Type | Protein |
| Sequence Length | 1560 aa |
Lysine-specific demethylase 5C
Review this target as Lysine-specific demethylase 5C, mapped to UniProt P41229. Sequence length is 1560 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4536443 | 8.23 | IC50 | 5.84 | Preclinical |
| CHEMBL4542928 | 8.21 | IC50 | 6.24 | Preclinical |
| CHEMBL5199483 | 8.06 | IC50 | 8.8 | Preclinical |
| CHEMBL3787669 | 8.0 | IC50 | 9.92 | Preclinical |
| CHEMBL3774692 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL5569973 | 7.87 | IC50 | 13.6 | Preclinical |
| CHEMBL4438830 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL4454253 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL3775040 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL3775451 | 7.68 | IC50 | 21.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 32 | 155 | 6.3 |
| cell-based format | 13 | 22 | 6.0 |
| assay format | 2 | 1 | 6.7 |