Compound Detail
CHEMBL5200888
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5200888 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JJUPLPWLNINRPU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
307.7
MW (Da)
3.60
ALogP
4
HBA
3
HBD
104.5
PSA (Ų)
0.59
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.17 | 4.17 | 68000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 68000.0 | nM | 4.17 | Inhibition of full length recombinant His6 tagged human RUVBL1/2 expressed in Es... | 35364523 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35364523 | 10.1016/j.bmc.2022.116726 | RuvB-like 1 | 1 |
| 35364523 | 10.1016/j.bmc.2022.116726 | RuvB-like 2 | 1 |
| 35364523 | 10.1016/j.bmc.2022.116726 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine