Compound Detail
CHEMBL5201452
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Basic Information
| ChEMBL ID | CHEMBL5201452 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JNHMBILIIONVKC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
275.3
MW (Da)
3.09
ALogP
5
HBA
0
HBD
61.6
PSA (Ų)
0.78
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 6.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RISC-loading complex subunit TARBP2 CHEMBL2098 | Kd | 6.17 | 6.17 | 679.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RISC-loading complex subunit TARBP2 | Kd | = | 679.8 | nM | 6.17 | Binding affinity to human recombinant TRBP by SPR assay | 35695407 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35695407 | 10.1021/acs.jmedchem.2c00189 | RISC-loading complex subunit TARBP2 | 1 |
Data from ChEMBL 36 via Core Engine