Compound Detail
CHEMBL5202109
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Basic Information
| ChEMBL ID | CHEMBL5202109 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GGEZNRLHFLVHQT-UHFFFAOYSA-N |
4
Targets
4
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
249.2
MW (Da)
3.59
ALogP
2
HBA
0
HBD
30.0
PSA (Ų)
0.48
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 4.82
Target Activity Profile
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| T-24 | IC50 | = | 15200.0 | nM | 4.82 | Antiproliferative activity against human T24 cells assessed as cell growth inhib... | 35092899 |
| MGC-803 | IC50 | = | 16200.0 | nM | 4.79 | Antiproliferative activity against human MGC-803 cells assessed as cell growth i... | 35092899 |
| SK-OV-3 | IC50 | = | 22300.0 | nM | 4.65 | Antiproliferative activity against human SK-OV-3 cells assessed as cell growth i... | 35092899 |
| HepG2 | IC50 | = | 30300.0 | nM | 4.52 | Antiproliferative activity against human HepG2 cells assessed as cell growth inh... | 35092899 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35092899 | 10.1016/j.ejmech.2022.114141 | T-24 | 2 |
| 35092899 | 10.1016/j.ejmech.2022.114141 | HepG2 | 1 |
| 35092899 | 10.1016/j.ejmech.2022.114141 | MGC-803 | 1 |
| 35092899 | 10.1016/j.ejmech.2022.114141 | SK-OV-3 | 1 |
| 35092899 | 10.1016/j.ejmech.2022.114141 | WI-38 | 1 |
Data from ChEMBL 36 via Core Engine