Compound Detail
CHEMBL520344
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL520344 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LLQODZTYTMHLOD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
367.5
MW (Da)
3.78
ALogP
7
HBA
1
HBD
71.2
PSA (Ų)
0.71
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.61
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 CHEMBL4649 | IC50 | 7.61 | 7.61 | 24.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | IC50 | = | 24.8 | nM | 7.61 | Displacement of [125I]Tyro-rat/human CRF from CRF1 receptor in rat cortical memb... | 19361209 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19361209 | 10.1021/jm900025h | Corticotropin-releasing factor receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine