Compound Detail
CHEMBL5204076
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Basic Information
| ChEMBL ID | CHEMBL5204076 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HRYMUBGCNLXLRG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
395.4
MW (Da)
1.54
ALogP
8
HBA
1
HBD
108.8
PSA (Ų)
0.72
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.74
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 143B CHEMBL614508 | IC50 | 5.74 | 5.74 | 1810.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 143B | IC50 | = | 1810.0 | nM | 5.74 | Antiproliferative activity against human 143B cells assessed as inhibition of ce... | 35476936 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35476936 | 10.1021/acs.jmedchem.2c00004 | 143B | 1 |
Data from ChEMBL 36 via Core Engine