Compound Detail
CHEMBL5208225
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Basic Information
| ChEMBL ID | CHEMBL5208225 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YWTCHPQZRNWWNO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
409.3
MW (Da)
3.51
ALogP
6
HBA
1
HBD
103.0
PSA (Ų)
0.39
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.59
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Androgen receptor CHEMBL1871 | IC50 | 5.59 | 5.59 | 2570.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Androgen receptor | IC50 | = | 2570.0 | nM | 5.59 | Antagonist activity at androgen receptor (unknown origin) in human LNCap-ARR2PB-... | 36154033 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36154033 | 10.1021/acs.jmedchem.2c00912 | Androgen receptor | 1 |
Data from ChEMBL 36 via Core Engine