Compound Detail
CHEMBL5209084
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Basic Information
| ChEMBL ID | CHEMBL5209084 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WXDZWCYHESLJBK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
412.5
MW (Da)
3.54
ALogP
6
HBA
0
HBD
60.2
PSA (Ų)
0.50
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte growth factor receptor CHEMBL3717 | IC50 | 7.38 | 7.38 | 41.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte growth factor receptor | IC50 | = | 41.6 | nM | 7.38 | Inhibition of N-terminal His/SUMO tagged wild type human c-Met (1038 to 1346 res... | 36355693 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36355693 | 10.1021/acs.jmedchem.2c00981 | Hepatocyte growth factor receptor | 1 |
Data from ChEMBL 36 via Core Engine