Compound Detail
CHEMBL524337
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Basic Information
| ChEMBL ID | CHEMBL524337 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YMGXXFGYKZICEJ-MVDHHOEZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
1545.7
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| J774.A1 CHEMBL614040 | IC50 | 5.05 | 5.05 | 9000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| J774.A1 | IC50 | = | 9000.0 | nM | 5.05 | Antiproliferative activity against mouse J774.A1 cells after 72 hrs by MTT conve... | 18442289 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18442289 | 10.1021/np8000464 | HEK293 | 1 |
| 18442289 | 10.1021/np8000464 | WEHI-164 | 1 |
| 18442289 | 10.1021/np8000464 | J774.A1 | 1 |
Data from ChEMBL 36 via Core Engine