Compound Detail
CHEMBL525350
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL525350 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FWIXOUMETCCFPO-SOFGYWHQSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
434.5
MW (Da)
5.95
ALogP
6
HBA
2
HBD
89.1
PSA (Ų)
0.49
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.34
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RAW264.7 CHEMBL612557 | IC50 | 4.34 | 4.34 | 46100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RAW264.7 | IC50 | = | 46100.0 | nM | 4.34 | Cytotoxicity against mouse RAW264.7 cells by MTT assay | 16643064 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16643064 | 10.1021/np0600346 | RAW264.7 | 3 |
| 34546736 | 10.1021/acs.jnatprod.1c00578 | Pseudomonas aeruginosa | 1 |
| 34546736 | 10.1021/acs.jnatprod.1c00578 | Escherichia coli | 1 |
| 34546736 | 10.1021/acs.jnatprod.1c00578 | Acinetobacter baumannii | 1 |
| 34546736 | 10.1021/acs.jnatprod.1c00578 | Klebsiella pneumoniae | 1 |
| 34546736 | 10.1021/acs.jnatprod.1c00578 | Enterococcus | 1 |
| 34546736 | 10.1021/acs.jnatprod.1c00578 | Staphylococcus aureus | 1 |
Data from ChEMBL 36 via Core Engine