Compound Detail
CHEMBL526279
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Basic Information
| ChEMBL ID | CHEMBL526279 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AHUNZWKOCMCDRA-VGOFMYFVSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
359.8
MW (Da)
4.97
ALogP
4
HBA
0
HBD
47.8
PSA (Ų)
0.38
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 5.16 | 5.16 | 7000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 7000.0 | nM | 5.16 | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7 ... | 19269069 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19269069 | 10.1016/j.ejmech.2009.02.008 | Plasmodium falciparum | 6 |
| 17977622 | 10.1016/j.ejmech.2007.09.014 | Plasmodium falciparum | 1 |
Data from ChEMBL 36 via Core Engine