Compound Detail
CHEMBL5270462
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5270462 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DVRAGXHGWAKYIU-WDZFZDKYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
283.3
MW (Da)
1.73
ALogP
4
HBA
2
HBD
84.1
PSA (Ų)
0.66
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen synthase kinase-3 beta CHEMBL262 | IC50 | 5.17 | 5.17 | 6720.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glycogen synthase kinase-3 beta | IC50 | = | 6720.0 | nM | 5.17 | Inhibition of recombinant human GSK3beta (636 to 661 residues) assessed as reduc... | 37054760 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37054760 | 10.1016/j.bmcl.2023.129283 | Glycogen synthase kinase-3 beta | 2 |
Data from ChEMBL 36 via Core Engine