Compound Detail
CHEMBL5271084
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5271084 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FNOMOLVTRWMYBZ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
256.5
MW (Da)
4.24
ALogP
2
HBA
2
HBD
38.0
PSA (Ų)
0.43
QED
0
Ro5 Violations
15
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Leishmania chagasi CHEMBL612790 | IC50 | 6.28 | 6.28 | 530.0 | 1 |
| Leishmania amazonensis CHEMBL612877 | IC50 | 5.29 | 5.29 | 5130.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Leishmania chagasi | IC50 | = | 530.0 | nM | 6.28 | Antiprotozoal activity against Leishmania chagasi measured after 3 days by MTT a... | 28886510 |
| Leishmania amazonensis | IC50 | = | 5130.0 | nM | 5.29 | Antiprotozoal activity against Leishmania amazonensis measured after 3 days by M... | 28886510 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28886510 | 10.1016/j.ejmech.2017.08.014 | Leishmania chagasi | 1 |
| 28886510 | 10.1016/j.ejmech.2017.08.014 | Leishmania amazonensis | 1 |
Data from ChEMBL 36 via Core Engine