Compound Detail
CHEMBL5279932
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Basic Information
| ChEMBL ID | CHEMBL5279932 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CJAGWEUXLWSNEX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
323.2
MW (Da)
2.12
ALogP
7
HBA
3
HBD
112.5
PSA (Ų)
0.68
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Taste receptor type 2 member 14 CHEMBL3309105 | EC50 | 5.17 | 5.17 | 6800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Taste receptor type 2 member 14 | EC50 | = | 6800.0 | nM | 5.17 | Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 a... | 36847646 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36847646 | 10.1021/acs.jmedchem.2c01997 | Taste receptor type 2 member 14 | 2 |
Data from ChEMBL 36 via Core Engine