Compound Detail
CHEMBL5283701
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5283701 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MXRZUXZAVSNBMD-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
341.4
MW (Da)
5.25
ALogP
2
HBA
1
HBD
42.1
PSA (Ų)
0.70
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 7.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 7.07 | 7.0433 | 86.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 86.0 | nM | 7.07 | Antiplasmodial activity against Plasmodium falciparum Dd2 infected in human Eryt... | 29360043 |
| Plasmodium falciparum | IC50 | = | 86.0 | nM | 7.07 | Antiplasmodial activity against Plasmodium falciparum D6 infected in human Eryth... | 29360043 |
| Plasmodium falciparum | IC50 | = | 102.0 | nM | 6.99 | Antiplasmodial activity against Plasmodium falciparum Tm90-C2B infected in human... | 29360043 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29360043 | 10.1016/j.ejmech.2018.01.039 | Plasmodium falciparum | 3 |
Data from ChEMBL 36 via Core Engine